, pp. -, 2016.
AbstractBackground Myocardial deformation assessed by two dimensional speckle tracking echocardiography (2D-STE) allows accurate evaluation of regional and global left ventricular (LV) function and is sensitive to detect abnormalities induced by ischemia. Aim To examine the value of \{LV\} strain (S) and strain rate (SR) assessed by \{STE\} to detect the presence, and extent of coronary artery affection in patients with suspected stable coronary artery disease (SCAD). Methods 81 patients with suspected \{SCAD\} and normal resting echocardiography were subjected to 2D-STE and coronary angiography. The peak systolic (PS) global longitudinal strain (GLS)/strain rate (GLSR) and \{PS\} global radial strain (GRS)/strain rate (GRSR) were calculated as the average of S/SR of the 18 \{LV\} segments of the 3 apical views. The \{PS\} mid circumferential strain (MCS)/strain rate (MCSR) was calculated as the average of S/SR of the 6 \{LV\} segments of the mid \{LV\} cavity short axis view. Results 20 patients (24.7%) represented the normal coronaries group (NCG), and 27 patients (33.3%) with one/two vessel-CAD represented the low risk group (LRG) while 34 patients (42%) with three vessel/left main-CAD represented the high risk group (HRG). GLS, GLSR, GRS, GRSR, \{MCS\} and \{MCSR\} were significantly lower in patients with significant \{CAD\} compared to \{NCG\} (all p = 0.000). GLS, GLSR, GRSR, \{MCS\} and \{MCSR\} were significantly lower in \{HRG\} compared to \{LRG\} (p = 0.03
