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2023
Khattab, A. Y., N. E. Awad, D. A. El Fadeel, and M. Fadel, "Dual antineoplastic and photodynamic effects of methanolic extract of Tecoma stans yellow flowers for cancer treatment", Journal of Herbmed Pharmacology, vol. 12, issue 3, pp. 432-441, 2023.
Khattab, A. Y., N. E. Awad, D. A. El Fadeel, and M. Fadel, "Dual antineoplastic and photodynamic effects of methanolic extract of Tecoma stans yellow flowers for cancer treatment", Journal of HerbMed Pharmacology, vol. 12, no. 3, pp. 432 – 441, 2023. AbstractWebsite
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Safwat, S. M., A. Khaled, A. Elawwad, and M. E. Matta, "Dual-chamber microbial fuel cells as biosensors for the toxicity detection of benzene, phenol, chromium, and copper in wastewater: Applicability investigation, effect of various catholyte solutions, and life cycle assessment", Process Safety and Environmental Protection, vol. 170, pp. 1121-1136, 2023.
Safwat, S. M., A. Khaled, A. Elawwad, and M. E. Matta, "Dual-chamber microbial fuel cells as biosensors for the toxicity detection of benzene, phenol, chromium, and copper in wastewater: Applicability investigation, effect of various catholyte solutions, and life cycle assessment", Process Safety and Environmental Protection, vol. 170: Elsevier, pp. 1121-1136, 2023. Abstract
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El Sheikh, M. A., P. M E Gaafar, M. A. Khattab, M. K. A Helwah, M. H. Noureldin, and H. Abbas, "Dual-effects of caffeinated hyalurosomes as a nano-cosmeceutical gel counteracting UV-induced skin ageing.", International journal of pharmaceutics: X, vol. 5, pp. 100170, 2023. Abstract

Caffeine (CAF) is a challenging natural bioactive compound with proven antiaging efficacy. However, being hydrophilic hampers its permeation through the skin. Our aim is to develop a novel CAF-loaded nano-cosmeceutical tool counteracting skin photoaging via improving CAF skin permeation using a bioactive nanocarrier. Caffeinated hyalurosomes are novel biocompatible antiaging nanoplatforms designed by immobilization of phospholipid vesicles with a hyaluronan polymer. Physicochemical properties of the selected hyalurosomes formulation showed nano-sized vesicles (210.10 ± 1.87 nm), with high zeta potential (-31.30 ± 1.19 mv), and high encapsulation efficiency (84.60 ± 1.05%). In vitro release results showed outstanding sustained release profile from caffeinated hyalurosomes compared to the CAF-loaded in conventional gel over 24 h. The in-vivo study revealed a photoprotective effect of caffeinated hyalurosomes, reflected from the intact and wrinkling-free skin. Results of biochemical analyses of oxidative stress, pro-inflammatory mediators, and anti-wrinkling markers further confirmed the efficacy of the prepared hyalurosomes compared to the CAF conventional gel. Finally, histopathological examination demonstrated normal histological structures of epidermal layers with minimal inflammatory cell infiltrates in the caffeinated hyalurosomes group compared to the positive control group. Conclusively, caffeinated hyalurosomes successfully achieved enhanced CAF loading and penetration into the skin besides the hydration effect of hyaluronan. Consequently, the developed delivery system presents a promising skin protection nano-platforms via the double effects of both hyaluronan and CAF, hence it guards against skin photodamage.

El-Hussieny, M., M. A. Abd-El-Maksoud, F. M. Soliman, M. A. Fouad, and M. K. El-Ashrey, "Dual-target ligand discovery for Alzheimer’s disease: triphenylphosphoranylidene derivatives as inhibitors of acetylcholinesterase and $\beta$-amyloid aggregation", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 38, no. 1: Taylor & Francis, pp. 2166040, 2023. Abstract
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El-Hussieny, M., M. A. Abd-El-Maksoud, F. M. Soliman, M. A. Fouad, and M. K. El-Ashrey, "Dual-target ligand discovery for Alzheimer’s disease: triphenylphosphoranylidene derivatives as inhibitors of acetylcholinesterase and $\beta$-amyloid aggregation", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 38, no. 1: Taylor & Francis, pp. 2166040, 2023. Abstract
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, "Dulaglutide impedes depressive-like behavior persuaded by chronic social defeat stress model in male C57BL/6 mice: Implications on GLP-1R and cAMP/PKA signaling pathway in the hippocampus", Life Sciences, vol. 320, 2023.
Kenawy, D. M., M. Elsisy, M. Abdel-Rasoul, T. L. Koppert, M. I. Garcia-Neuer, Y. Chun, and B. W. Tillman, "A dumbbell rescue stent graft facilitates clamp-free repair of aortic injury in a porcine model", JVS-Vascular Science, vol. 4: Elsevier, pp. 100100, 2023. Abstract
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Ahmed, M. R., A. E. Damatty, K. Dai, and W. Lu, "Dynamic Analysis of Horizontal Axis Wind Turbines under Thunderstorm Downbursts", Journal of Structural Engineering, vol. 149, 2023.
Bakkar, A. R., A. Elyamani, A. G. El-Attar, D. V. Bompa, A. Y. Elghazouli, and S. A. Mourad, "Dynamic Characterisation of a Heritage Structure with Limited Accessibility Using Ambient Vibrations", Buildings, vol. 13, no. 1, 2023. AbstractWebsite

Historic Cairo has been a UNESCO World Heritage Site since 1979. It has more than 600 historic structures, which require extensive studies to sustain their cultural, religious, and economic values. The main aim of this paper is to undertake dynamic investigation tests for the dome of Fatima Khatun, a historic mausoleum in Historic Cairo dating back to the 13th century and consisting of mainly bricks and stones. The challenge was that the structure was difficult to access, and only a small portion of the top was accessible for the attachment of accelerometers. Current dynamic identification procedures typically adopt methods in which the sensors are arranged at optimal locations and permit direct assessment of the natural frequencies, mode shapes, and damping ratios of a structure. Approaches that allow for the evaluation of dynamic response for structures with limited accessibility are lacking. To this end, in addition to in situ dynamic investigation tests, a numerical model was created based on available architectural, structural, and material documentation to obtain detailed insight into the dominant modes of vibration. The free vibration analysis of the numerical model identified the dynamic properties of the structure using reasonable assumptions on boundary conditions. System identification, which was carried out using in situ dynamic investigation tests and input from modelling, captured three experimental natural frequencies of the structure with their mode shapes and damping ratios. The approach proposed in this study informs and directs structural restoration for the mausoleum and can be used for other heritage structures located in congested historic sites.

Saad, D. A., M. A. El-Motaleb, and H. Osman, "Dynamic Conceptual Model of the Real Estate Sector Growth Considering Behavioral Biases", 9th CSCE/CRC International Construction Specialty Conference, Moncton, Canada, Canadian Society of Civil Engineering, 2023.
Koko, R. R. Z., I. A. Yassine, M. A. Wahed, J. K. Madete, and M. A. Rushdi, "Dynamic Construction of Outlier Detector Ensembles With Bisecting K-Means Clustering", EEE Access, vol. 11, pp. 24431-24447, 2023.
Koko, R. R. Z., I. A. Yassine, M. A. Wahed, J. K. Madete, and M. A. Rushdi, "Dynamic construction of outlier detector ensembles with bisecting k-means clustering", IEEE Access, vol. 11, pp. 24431-24447, 2023.
Mostafa, B., M. Molnar, M. Saleh, A. Benslimane, and S. Kassem, "Dynamic Distributed Monitoring for 6LoWPAN-based IoT Networks", INFOCOMMUNICATIONS JOURNAL, vol. 15, no. 1, pp. 64–76, 2023. Abstract
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Mostafa, B., M. Molnar, M. Saleh, A. Benslimane, and S. Kassem, "Dynamic Distributed Monitoring for 6LoWPAN-based IoT Networks", INFOCOMMUNICATIONS JOURNAL, vol. 15, issue 1, pp. 64-76, 2023. Abstract
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Saleh, M., B. Mostafa, M. Molnar, and S. Benslimane, Abderrahim and Kassem, "Dynamic Distributed Monitoring for 6LoWPAN-based IoT Networks", INFOCOMMUNICATIONS JOURNAL, vol. 15, pp. 64-76, 2023. infocomjournal_dynamic_distributed.pdf
4. Sherien M. El‐Daly, Mona A. El‐Bana, S. A. E. - R. Y. A. L. D. M. S., "Dynamic expression of H19 and MALAT1 and their correlation with tumor progression biomarkers in a multistage hepatocarcinogenesis model", Cell Biochemistry & Function, vol. 2, issue 2, pp. 1-17, 2023. cell_biochemistry___function_-_2023.pdf
El-sefy, M., A. Yosri, A. Siam, W. El-Dakhakhni, S. Nagasaki, and L. Wiebe, "A dynamic probabilistic risk assessment platform for nuclear power plants under single and concurrent transients", Journal of Nuclear Science and Technology, 2023.
Badr, A., Z. Li, and W. El-Dakhakhni, "Dynamic resilience quantification of hydropower infrastructure in multihazard environments", Journal of Infrastructure Systems, vol. 29, issue 2: American Society of Civil Engineers, pp. 04023012, 2023. Abstract
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, Dynamical analysis of an inverted pendulum with positive position feedback controller approximate uniform solutionhttps://www.nature.com/articles/s41598-023-34918-x, , 2023.
Tripathy, A., S. Sahoo, H. Rezazadeh, Z. P. Izgi, and M. S. Osman, "Dynamics of damped and undamped wave natures in ferromagnetic materials", Optik, vol. 281, pp. 170817, 2023.
Abdel-Gawad, H. I., "Dynamics of steady, unsteady flows and heat transfer in Casson fluid over a free stretching surface: stability analysis", Waves in Random and Complex Media: Taylor & Francis, pp. 1–19, 2023. Abstract
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Mostafa, A., D. Sabry, nesreen aburaia, A. Fawzy, and amany abuelela, "Dyslipidemia initiates keratinocytes proliferation through upregulation of lncRNA NEAT in psoriasis patients.", Mol Biol Rep. , vol. 9, issue 50, pp. 7597-7604, 2023. psorisis_paper.pdf
Mostafa, A., D. Sabry, N. Aboraia, A. Fawzy, and A. A. Abou-Elalla, "Dyslipidemia initiates keratinocytes proliferation through upregulation of lncRNA NEAT in psoriasis patients.", Molecular biology reports, vol. 50, issue 9, pp. 7597-7604, 2023. Abstract

BACKGROUND: Psoriasis is a chronic inflammatory immune-mediated and hyper proliferative skin disorder that has underlying genetic factors. Psoriasis can result from interaction of cytokines between keratinocytes and T-lymphocytes. NEAT is a lncRNA involved in immune modulation and has been previously studied in cancers. This study aims to clarify the unprecedented role of NEAT in psoriasis pathogenesis.

METHODS: The study was conducted on 50 healthy control subjects and 50 psoriasis patients. Blood samples from all participants were collected for analysis of their lipid profile. qRT-PCR was done for lncRNA NEAT, TNF-α, VEGF genes expression. The levels of ROS and caspase-3 were estimated by ELISA. ROC analysis was done to detect the diagnostic value of lncRNA NEAT gene expression.

RESULTS: Dyslipidemia is more prevalent among psoriasis patients. A significant up regulation in lncRNA NEAT, TNF-α, VEGF genes expression (p value˂0.001) in psoriasis patients in addition to significant increase in ROS and caspase-3 levels (p value˂0.001) in compare to controls. Additionally, a positive significant correlation between TNF-α, ROS, NEAT, caspase-3 and dyslipidemia. NEAT had an area under the curve (AUC) of 0.931 (95% CI 0.844-0.978, p < 0.001).

CONCLUSION: Dyslipidemia is an initiating signal in psoriasis pathogenesis that creates a state of chronic inflammation and oxidative stress. This state induces keratinocytes proliferation and release of NEAT with subsequent caspase-3 activation to counteract the proliferating cells. NEAT could be considered as a good diagnostic biomarker for psoriasis.

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