Khayyal, M. T., N. I. Girgis, and E. McConnell,
"The use of penicillamine as an adjuvant to tartar emetic in the treatment of experimental schistosomiasis.",
Bulletin of the World Health Organization, vol. 37, issue 3, pp. 387-92, 1967.
AbstractOne of the principal drawbacks of antimonial therapy in schistosomiasis has been the prevalence of annoying, and sometimes dangerous, side-effects. The adjuvant administration of chelating agents offers a possible solution to this problem, providing this can be achieved without appreciably decreasing the therapeutic effect of the drug.The authors found that the chelating agent penicillamine lowered the toxicity of tartar emetic for mice and hamsters without affecting the tissue uptake of antimony. When administered in a similar manner to hamsters infected with Schistosoma mansoni there was no effect on the uptake of antimony by the parasites, or on the cure rate. This suggests a potential usefulness of penicillamine in antimony therapy.
Khayyal, M. T., N. I. Girgis, and E. McConnell,
"The use of penicillamine as an adjuvant to tartar emetic in the treatment of experimental schistosomiasis.",
Bulletin of the World Health Organization, vol. 37, issue 3, pp. 387-92, 1967.
AbstractOne of the principal drawbacks of antimonial therapy in schistosomiasis has been the prevalence of annoying, and sometimes dangerous, side-effects. The adjuvant administration of chelating agents offers a possible solution to this problem, providing this can be achieved without appreciably decreasing the therapeutic effect of the drug.The authors found that the chelating agent penicillamine lowered the toxicity of tartar emetic for mice and hamsters without affecting the tissue uptake of antimony. When administered in a similar manner to hamsters infected with Schistosoma mansoni there was no effect on the uptake of antimony by the parasites, or on the cure rate. This suggests a potential usefulness of penicillamine in antimony therapy.
Khayyal, M. T., N. I. Girgis, and E. McConnell,
"The use of penicillamine as an adjuvant to tartar emetic in the treatment of experimental schistosomiasis.",
Bulletin of the World Health Organization, vol. 37, issue 3, pp. 387-92, 1967.
AbstractOne of the principal drawbacks of antimonial therapy in schistosomiasis has been the prevalence of annoying, and sometimes dangerous, side-effects. The adjuvant administration of chelating agents offers a possible solution to this problem, providing this can be achieved without appreciably decreasing the therapeutic effect of the drug.The authors found that the chelating agent penicillamine lowered the toxicity of tartar emetic for mice and hamsters without affecting the tissue uptake of antimony. When administered in a similar manner to hamsters infected with Schistosoma mansoni there was no effect on the uptake of antimony by the parasites, or on the cure rate. This suggests a potential usefulness of penicillamine in antimony therapy.
Abdel-Fattah, A., M. Refai, and Z. El-Gothami,
"Tinea capitis in Egypt.",
Mykosen, vol. 10, pp. 189-194 , 1967.
AbstractZusammenfassung
In den letzten zwei Jahren wurden 250 Fälle von Kopfpilzerkrankungen mykologisch untersucht. In 172 Fällen konnte der Erreger kulturell nachgewiesen werden. In 92 Fällen (53,3%) wurde Trichophyton violaceum isoliert, in 46 Fällen (26,7%) war Trichophyton schoenleinii der Erreger, in 32 Fällen (18,8%) Microsporum canis. Trichophyton mentagrophytes und Trichophyton tonsurans wurden je einmal isoliert. Microsporum audouinii wurde nicht angetroffen.
Aus einer Übersicht über die Literatur ergibt sich, daß Trichophyton violaceum der häufigste Erreger der Kopfpilzerkrankungen in Ägypten ist.
]